Natalie O’Neill

Natalie O’Neill

Best azelaic acids (OTC & prescription)

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Natalie O’Neill
Feb 06, 2026
∙ Paid

I’m a huge advocate for azelaic acid for most skin types, but especially those prone to acne of all kinds (hormonal, sensitive skin, the list goes on!), so here’s a roundup the best azelaic acid serums, gels, and creams available right now.

New to azelaic acid entirely? I'd read my azelaic acid deep dive first — it covers how it works, who should use it, and how to introduce it.

Let’s start by looking at prescription vs non prescription formulas.

Best prescription azelaic acid for acne

You can either get prescription-strength azelaic acid from your GP or doctor, or an online pharmacy. Check out this guide I made on how to obtain prescription azelaic acid, because sometimes, actually getting it can feel really difficult.

1. Finacea gel 15%

Finacea is the brand my dermatologist recommended me to get and I find it really easy to use and get along with.

Finacea gel 15%

I really notice its anti-inflammatory properties because it helps calm my perioral dermatitis so well, and helps me tolerate my retinoid with less skin irritation.

My skin texture was already quite smooth so I can’t say it has changed that too much, because my retinoid keeps it in check. However, my friends who use it have also reported back to me that its done a lot for their texture.

Finacea gel 15% feedback

It’s a white ‘gel’ that actually looks more like a cream. I apply a pea-sized blob after cleansing, every other day.

video tutorial on how I apply it here

I prefer to use it in the evening because I do notice it sometimes leaves white ‘streaks’ on my face. Not ideal, but it’s so worth it for me as they kind of ‘melt’ away with other serums anyway, etc.

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2. Skinoren 20% cream

Skinoren is another popular prescription azelaic acid cream that’s often used for rosacea symptoms and acne management.

Skinoren 20% cream

I haven’t personally used it but I often read good things about it on Reddit.

20% is the strongest azelaic acid you can get, and, although it does sound quite high, azelaic acid is overall quite a gentle active. So all in all, I wouldn’t be scared if you have been prescribed it. However, I might not choose it to start with, personally.

Best over-the-counter azelaic acid for acne

Over-the-counter azelaic acid can be just as effective as prescription azelaic acid for acne-prone skin and uneven skin tone. This is because you can get the same strengths in both OTC and prescription.

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